Most B12 supplements unfortunately contain cyanocobalamin. In order for B12 to be utilized in the body, the liver must first remove the cyanide molecule and attach a methyl group to form “methylcobalamin”—the biologically active, tissue-ready form. Research has shown that methylcobalamin is more efficiently used and retained in the body than the cyanocobalamin form. Methylated B12/Folate utilizes methylcobalamin and includes a concentrated and bioavailable source of B12 and folate. Each tablet provides 5,000 mcg of methylcobalamin and 1,000 mcg of folate as Quatrefolic® (100% as 5-MTHF). This synergistic blend of methyl-donating B vitamins in Methylated B12/Folate quickly boosts tissue and brain levels to support numerous systems in the body.*
Vitamin B12 has been shown to be beneficial for maintaining a positive mental outlook; specifically, B12 acts as a methyl donor and increases the synthesis of SAM-e, a nutrient that has powerful mood and sleep-cycle regulating properties. Because of its ability to increase the production of neurotransmitters and nerve cell transmission, B12 has also been shown to improve cognitive function.*
Furthermore, Methylated B12/Folate can also help patients who are deficient in B12. Because of its role in the production of cellular energy, B12 deficiency is often characterized by fatigue and weakness. Supplementation with methylcobalamin and 5-MTHF—like the formulation contained in Methylated B12/Folate—has been shown to promote increased energy levels. Both 5-MTHF and methylcobalamin are also required to maintain optimal homocysteine balance, which is crucial for supporting arterial and cardiovascular health. In addition, 5-MTHF and methylcobalamin support healthy arterial blood flow by increasing nitric oxide production. Both are also required nutrients for the biosynthesis of melatonin (the hormone that helps induce sleep). Several studies have demonstrated that supplementation with methylcobalamin modulates melatonin secretion and helps to normalize the sleep-wake cycle.*
*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.